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Results highlight that the inactivation kinetics does not depend linearly on pressure but, due to the distribution of individual cell resistance in the sample, the efficacy of the treatment at higher pressures or upon multiple passes is reduced.
We confirmed in a large, very homogenous study sample the efficacy and safety of PLD/GEM combination in chemotherapy-naïve recurrent/metastatic breast cancer patients.
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However, this study only has a limited sample size: the efficacy population was base on 41 patients per protocol.
For each blood sample collected, the efficacy and toxicity scores, as well as the Dose considered, were the ones corresponding or reported at the time of sampling.
Comparison of the pre-treatment core biopsy and the post-treatment surgical sample establishes the efficacy of the experimental therapy often using change in tumor cell proliferation as a primary end-point [ 11- 15].
If in an efficacy test of an antiseptic product, neutralization validation is performed with a very short storage time after sampling, and the efficacy test itself has a long storage time after sampling, this may well result in a lower number of surviving test organisms indicating better efficacy of the antiseptic product which could be classified as a false-positive efficacy result.
Certain voluntary human participant pool procedures (e.g. where the participant selects when to participate in experiments) can compromise the representativeness of samples and the efficacy of random assignment procedures.
The findings demonstrated abnormal D-FISH results for 24 of 25 AFF19MLL, 19 of 20 MLLT4/MLL, all 20 MLLT3/MLL, all 18 MLL/ELL, and all 20 MLL/MLLT1 samples, confirming the efficacy of these D-FISH assays in detecting these common MLL/partner translocations.
Thus the measurement of the standard samples proves the efficacy of this technique.
Four clinical trials (2 with very small samples) examined the efficacy of e-cigarettes for smoking cessation.
These findings may help to explain the high frequency of PI3K pathway activation in HPV+ HNSCC samples and the efficacy of mTOR inhibitors in xenograft studies with HPV+ cell lines previously reported [ 33].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com