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Using mobile phones for data collection will for instance not be able to address issues such as household access, selecting an appropriate sample that permit generalization of findings, or the complexities of clustered sampling to reflect population statistics.
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The nationwide coverage since 1978 provides sample sizes that permit studies of rare diseases, disease complications, and effects in subgroups of patients (effect modification and interactions).
Future studies may consider larger sample sizes that permit more extensive analyses (ie, baseline total lesion area ≥250 mm and <500 mm).
However, these earlier studies have limitations that prevent their results from being applied more generally, e.g. they lack the sample replication that permits statistical analysis with sufficient power.
We aim to gain a sample size that permits a small to moderate effect size between SCM and TAU to be detected with a statistical power of 80%.
Solid-phase microextraction (SPME) is a powerful, simple, fast and an equilibrium-based sample preparation method that permits integration of sampling, sample clean-up, and pre-concentration in a single solvent-free step for chemical analysis.
MD is a bedside in vivo sampling technique that permits continuous analysis of a patient's interstitial fluid chemistry.
In vivo microdialysis (MD) is a bedside sampling method that permits continuous analysis of a patient's extracellular tissue chemistry without consuming blood.
Microdialysis (MD) is a bedside in vivo sampling technique that permits continuous analysis of a patient's interstitial fluid chemistry without consuming blood.
The study's main strength is the prospective collection of multiple biological samples that should permit the diagnosis of etiological agents involved in pneumonia as well as the importance of colonization by other microbial agents.
Under very general conditions the type I error rate is preserved under sample size adjustable schemes that permit a raise.
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