Establishing cross-discipline consensus concerning appropriate messages for women with RA regarding medication safety is an important avenue for future research that we are now pursuing.> This study has several strengths, including the national sample that comprised participants from metropolitan, regional and remote areas.
The findings of our study are of course limited by the relatively small sample size and the heterogeneity of the study sample that comprised healthy subjects as well as patients with schizophrenia, bipolar I disorder, and obsessive-compulsive disorder.
Strengths of our analysis include our nationally representative sample that comprised a diverse population of patients likely to be found in other parts of Africa, such as adolescents and elderly patients, patients suffering from conflict and food insecurity, and patients who switched treatment after initiation.
We elucidated the complete small RNA transcriptome of normal and malignant B cells through deep sequencing of 31 normal and malignant human B-cell samples that comprise the spectrum of B-cell differentiation and common malignant phenotypes.
In recent human studies, this approach typically has been applied in genome-wide association studies (GWASs) of large, population-based samples that comprise both case subjects (i.e., individuals expressing the trait, or phenotype, under investigation) and unaffected control subjects.
As the cellular composition of a tumor biopsy can differ depending on the tissue sampling method used [ 58], we sought to compare the metagene score distributions between the surgically acquired tumor specimens that we previously used to derive the metagenes (n = 1,954 tumor samples) [ 36] and the confirmed FNA biopsy samples that comprise the majority of the current study (n = 482 tumor samples).
This is likely to have arisen by the differences in cellular composition as the primary tumour samples contained a milieu of haematopoietic cells, including human erythrocytes that were absent in the xenograft samples that comprised of mononuclear cells derived from the murine spleen.
After an extensive review of published literature, we selected five miRNAs (miR-21, miR-141, miR-155, miR-183 and miR-200b) with putative diagnostic and prognostic value (Jeronimo and Henrique, 2011; Henrique et al, 2012), and tested them in a relatively large set of tissue samples that comprised the major histological subtypes.
The characteristics of the sample that comprise the total SNAC study closely reflects those of the general population of elderly people in Sweden.
The MSPD extraction method of compounds is a preparation method that comprises sample homogenization, cellular disruption, fractionation and purification in a single process.
The American Industrial Hygiene Association (AIHA) exposure assessment guide (Mulhausen and Damiano 1998) cautions against ignoring air sample results that comprise the upper tail of an individual's exposure distribution, especially when comparing it to PELs and OELs.
