Your English writing platform
Discover LudwigExact(1)
There is the implicit assumption in those studies that if large enough numbers of SNPs and large enough sample sizes of animals are used then high predictive accuracy will be obtained.
Similar(59)
Firstly, the small sample size of animals used in this study limited the statistical power.
The other limitation was that the data were derived from a small sample size of animals (three mice per group).
The lack of statistical significance may be due to the relatively small sample size of animal groups affecting statistical power.
It would be possible to continue to use sample sizes of 48-50 animals, but subdivide these into groups of 12 animals of 4 different strains (48 animals total) per dose/sex group, for example, instead of 48 identical animals.
More than 30% of chemicals tested failed to detect statistically significant dose response trends for tumors because of inadequate sample sizes of 50 animals per dose.
Reaching intergroup differences with 80% power at a probability of 5% would require sample sizes of 30 animals or more in each group.
Previous studies regarding CHD, based on sample sizes of 150-800 andmals and using microsatellites [ 14, 15] or SNPs [ 16– 19], have shown inconsistent results for QTL position depending on the breeds, density of markers, allele frequencies and statistical methods used.
We also notice as a shortage the sample sizes of only five animals in each group examined for LIS.
For each MWCNT formulation, a sample size of 48 animals was used, with 6 animals per dose (including sham control) and 24 per time point.
For the 158 individual experiments, 65.8% showed statistically significant activity at the experiment level (p < 0.05, Figure 2 figure supplement 1), with an average sample size of 8.03 animals per treatment arm and 8.39 animals per control arm.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com