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Calculation of sample size was performed using G*Power Software (version 3.0.10, Germany) [20].
No formal sample size was performed.
Calculation of sample size was performed by an online calculator (http://sampsize.sourceforge.net/iface/index.html).html
Moreover, a test of sensitivity of model choice to sample size was performed using simulation methods.
Analysis of estimated sample size was performed and yielded a power of 90%.
No formal determination of sample size was performed and no formal statistical comparisons were made between the dose groups.
Similar(46)
Calculations of the sample size were performed as described by A'Hern [ 8], Simon [ 9] and Fleming [ 10].
Thus, no estimations of power or sample size were performed considering the changes in the density of subchondral mineralized tissue.
All statistical calculations including calculations of power and sample size were performed with the program Statistica® (StatSoft Europe GmbH, Hamburg, Germany).
A nonparametric multivariate analysis of variance for repeated measurements and small sample sizes was performed.
Comparison of normal data with identical sample sizes was performed using one-way ANOVA with Bonferroni post-test.
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