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The sample size depended on the number of animals allocated for scientific studies with the selection being done at random by gun stunning.
The sample size depended on the number of stroke survivors choosing the new services, which limited the formal sample size calculation based on the treatment effect size.
Since the primary objective of the trial was to determine the safety and tolerability of MK-2206 in combination with trastuzumab, the trial sample size depended primarily on clinical rather than statistical considerations.
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Methods to estimate sample size depend on statistical theory.
The necessary sample size depends on the required precision of the estimated SL.
Sample size depends on the prevalence of the disorder and the precision of the estimates needed, the latter being related to the purpose of the study.
For a design involving cluster sampling, the appropriate sample size depends on the so-called design effect, which is a function of the average cluster size and the intracluster correlation coefficient (ICC).
The decision to switch between maximum and minimum sample size depends on position of the prior sample point on the control chart and summarizes as following function: n ( i ), w ( i ), k ( i ) = n 1, w 1, k 1 n 2, w 2, k 2 if if 0 ≤ T i - 1 2 ≤ w i - 1 w i - 1 < T i - 1 2 ≤ k i - 1 (5).
Therefore, the sample size depends on the desirability of the study.
Not surprisingly, the sample size depends strongly on the assumed magnitude and pattern of the treatment effect.
However, the actual interim look may be taken at a different sample size, depending on recruitment progress and funding.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com