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A number of references emphasize that the restricted-maximum-likelihood method for estimation of regression weights works well in small sample settings, and there are a number of exemplary multilevel applications that refer to small sample sizes at Level 2 (N = 15 20) (e.g., Kenward and Roger 1997; McNeish and Stapleton 2016; Skene and Kenward 2010; Stegmueller 2013).
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Sampler settings and sampling intervals are summarised in Table 7.
However, comparing QI pass rates should be done with caution because the study samples, settings and methods may differ.
It is difficult to compare the dust mite and cat allergen levels between studies due to different study populations and dust sampling settings and methods (e.g., vacuum cleaner used, filter size, time and area sampling).
A short form of their original scale, the Ego Resilience Scale 89 (ER89) (Block and Kremen 1996) has later been used on various samples, settings and age groups (Bonanno et al. 2011; Cohn et al. 2009; Ong et al. 2006, 2010; Sahdra et al. 2011; Schaubroeck et al. 2011; Sherman et al. 2010).
The instability is even worse in small sample settings (Braga-Neto and Dougherty, 2004).
This does not take into account feature-selection, which is commonplace in high-dimensional and small sample settings.
No overall conclusion of the current resistance situation in the ambulatory sector in Austria can be gathered out of these different studies due to the differences in sampling settings, inclusion and exclusion criteria of the study population, time periods, bacteria analysed and the methodology used.
In total, 21 publications met the inclusion criteria and were included in the review (online Tables DS1 4 give details of samples, settings, methods and findings).
Evaluation of these tools has been restricted to narrow samples or settings, and there is no tool with strong reliability and validity applicable across a range of settings.
Therefore, we suspected that heterogeneity will be reduced by considering more studies for the SAA test, which might reduce the effect of different sampling, clinical settings, and other heterogeneity-caused factors.
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