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Firstly, the use of a convenience sample restricts the generalisability of our results to the wider population, however this was deemed necessary in order to recruit sufficient numbers of the target population.
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The number of cases in the sample restricted the predictors included in the model.
This correction is required because in most cases, the limited number of samples restricts the number of distinct permutations performed, thus leading to the incorrect attribution of 0 values to the estimation of certain p-values.
The indices of relatedness were also calculated on reduced sets of samples restricting the portion of admixture genotypes.
Further, although there were often large relative differences between the two groups (LAT vs HAT), the limited number of samples restricted the statistical power.
#: The sample restricted to the condition of hypertension, myocardial infarction, and congestive heart failure $: Condition chosen first, with random selection of controls without the condition of interest.
A confirmatory factor analysis was performed using the combined sample restricted to the seven items selected for the final CASIS.
Also, the prevalence of IgE-positive case status increased in dose-responsive manner per quartile PGE exposure unit (Figure 3) in the sample restricted to the cases only.
The relatively small sample size restricts the scope of analyses that can be conducted.
Further limitations arise from the Caucasian study sample, which restricts the generalizability of our results.
However, the limited sample size restricts the number of variables to be included in the PS regression model to limit model over parameterization.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com