Sentence examples for sample requires significant from inspiring English sources

Thus, even if SWIFT clustering of the consensus sample requires significant time, e.g. 2 h (see Supporting Information for sample run times), analysis of hundreds of samples can be completed rapidly.

However, tissue-based biomarkers are more difficult to establish and to transfer into the clinic as sampling requires significant intervention.

The problem is that even the locations of each fragment within gp120 vary between samples, requiring significant manual curation to prepare the sequences for comparison.

MS is powerful in terms of scope, but this approach requires significant sample preparation and cannot be used to directly identify Ub chains in their cellular context.

The inherent biological noise, combined with sample error in these experiments, requires significant biological replication to appropriately power such experiments, and even when appropriately powered, false discovery rates still remain relatively high [ 39].

Screening programs can be employed to archive serial samples but require significant efforts to collect samples and auxiliary data for marker research.

Sample collection is invasive; sample collection may be restricted to trained professionals by legislation and often requires significant operator skill.

Discovering protein biomarkers is not trivial and requires significant analytical methodology to enable sufficient separation of highly complex biological samples.

The deck requires significant landscaping.

This requires significant gain.

It requires significant personnel resources.