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Thus the potential effects of sample polarization versus fundamental pump beam polarization were minimized.
Note that for this detection geometry, there are no specular reflection effects, thus enhancing sensitivity to bulk sample polarization properties.
The current method takes advantage of the sample polarization properties and extracts setup effects from polarization changes caused by birefringent tissue structures.
In addition to imaging based on tissue reflectivity, PS-OCT also enables depth-resolved mapping of sample polarization properties such as phase-retardation, birefringent axis orientation, Stokes vectors, and degree of polarization uniformity (DOPU).
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The optical set-up is based on a polarization states generator (PSG -sample-polarization states analyzer (PSG -sample-polarizationcan be adaPSG -sample-polarizationstatess well analyzerflection mode.
In biological samples, polarization-dependent SHG microscopy has been used to great effect in the analysis of collagen, cell membranes, and other ordered biological motifs, and has been extended to in vivo studies of cancer, musculoskeletal disorders, cardiovascular disease, and corneal disorders.
Imaging the sample's polarization properties has enabled additional image contrast and quantitative measurements.
A hybrid PM/SM fiber based system, using a predefined sampling beam polarization state, has been reported [ 35].
We studied the staining pattern of all the samples by polarization light microscopy after treatment of KMnO4 to determine the type of amyloidosis.
However, in contrast to the reported LT results, we could not detect statistically significant differences in Stark effects for aligned (Δλ = 0.7 ± 1.4 nm) and nonaligned (Δλ = 0.6 ± 1.2 nm) samples, although polarization measurements suggested otherwise (SI-3).
In contrast to SD-OCT, polarization-sensitive OCT is capable of gathering additional information on the sample using the polarization properties of light.
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