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Table 3 shows the sample p values.
For cross-sectional analyses, the lowest index was used for patients with >1 available index sample; p values were calculated using a Wilcoxon rank sum test.
The mean unadjusted disutility associated to CKD stage 5 compared to CKD stage 1 2 was Δ= −0.22 (p<0.01) in the pooled sample, Δ= −0.25 in the UK sample (p=0.01) and Δ= −0.09 (p=0.04) in the US sample (p values based on 1-way ANOVA, pre-specified linear contrast).
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*p = 0.0001 for eschar swab sample vs. skin biopsy sample; p value not available for other parameters.
Accordingly, the GATA motif is the top motif enriched in the HudsonAlpha sample (P value < 1 e −1216), whereas the REST-NRSF motif is the top enriched motif in the Broad sample (P value < 1 e −275).
The fact that randomly picked locations had slightly higher Ct values in the VPA sample (p value = 1.1e−11) compared to vehicle may reflect a general effect on chromatin accessibility after VPA treatment.
We also examined the CNV content of the 1000 PDx controls and observed a significantly higher average number of CNVs per sample (p value < 2.2e-16) compared with the ASD cases (Table 1).
Regression results showed consistent and robust association between sanitation success and education for the national, rural and socio-political samples (p values 0.018 0.038).
Statistical significance was evaluated by Student's t-test for paired samples; p values <.05 (two-sided) were considered statistically significant.
LS re-sampling P values were <10−5 for both user-defined gene sets selected with different cutoffs to define the acquired resistance signature (i.e., for 2,446 and 633 genes).
We cannot, however, reject the null hypothesis of a 5percentt impact based on the pooled sample (p-value of 0.14).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com