Exact(1)
As the individual sequenced genomes sample only a limited proportion of the variation within-species, some mutations, especially low-frequency mutations such as some TE insertions, are unlikely to be discovered.
Similar(59)
In this work we investigate the possibility of combining approaches from statistical modeling and bio-inspired algorithms to effectively explore a huge search space, sampling only a limited number of experimental points.
For some samples only a limited amount of DNA was available.
While H. hepaticus was detected in bile samples only a limited number were present and these were in the coccoid form.
In order to comply with guidelines regarding the conduct of genetic research on stored tissue samples, only a limited amount of clinical data was extracted from the medical record, including age at diagnosis (< 50 or ≥ 50 years), tumor size (≤ 2 cm or > 2 cm), lymph node involvement (present or absent), hormone receptor status (if available), and adjuvant treatment with chemotherapy or tamoxifen.
Despite the mechanistic evidence for codon usage bias, and the known association between codon usage bias and high gene expression, the majority of studies investigating selection on synonymous codons in mammals have focused on genome-wide patterns and have sampled only a limited diversity of mammal species (for review see [ 5, 6]).
Because of the small sample size, only a limited number of variables could be tested.
Because of the relatively small sample size, only a limited number of covariates could be incorporated into the regression models.
Third, because of our small sample size, only a limited number of covariates could be included in our regression models; the inclusion of additional potential confounders would have increased the possibility of obtaining unreliable results due to overfitting.
Because persons who died were not sampled postmortem, only a limited number of clinical samples were collected (Table 1).
Indeed, since usually signal samples assume only a limited range of values, an attacker will be easily able to decrypt the ciphertexts, or at least to derive meaningful information about them.
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