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At every third generation, we also selected a random sample of functional mutants for sequencing.
Here we report the effects in the same sample of functional polymorphisms in MAOA and 5HTTLPR.
The EFST has been validated previously using a community-based sample of functional adults aged 60 + years [ 23].
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The GO annotations for the unigenes showed a fairly consistent sampling of functional classes, indicating that these SNP markers represent genes with different molecular functions and that they are involved in various different biological processes.
Surface generation and sampling of functional data to anatomical surfaces followed a similar procedure as described in Glasser et al.49 and Wig et al.50 First, following volumetric registration, anatomical surfaces were generated from the subject's MP-RAGE image using FreeSurfer's default recon-all processing pipeline (version 5.0).
In more general terms, we believe that the decision of which task condition to use for ROI based sampling of functional connectivity during steady-state conditions should be made with a consideration of which cognitive hypothesis one wishes to test.
GO annotations for the differentially expressed genes showed fairly consistent sampling of functional classes.
However, these differences are probably the result of uneven sampling of functional genotypes among these arbitrary age ranges.
Also, analysis of GO annotations for the Stenogyne unigenes showed a fairly consistent sampling of functional classes as defined for the Arabidopsis proteome (Fig. 3).
A summary with the number of unigenes annotated in each GO slim term is shown in Figure 5. GO annotations for the unigenes showed fairly consistent sampling of functional classes.
Coding-region SNPs are useful markers for mapping studies and for genome wide screens for signatures of selection, and we were able to identify putative SNP markers in nearly 4,000 unique contigs representing a broad sampling of functional categories.
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