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To conclude, we used VBM to investigate subtle neuroanatomical differences in developmental prosopagnosia, using a relatively large sample of developmental prosopagnosics compared with matched controls.
But like the functional neuroimaging studies of developmental prosopagnosia discussed above, this study had a relatively small sample of developmental prosopagnosics.
Our sample of developmental dyscalculia students did not have any reading difficulties and there were no differences in the scores of any reading tests compared with the control group (for more details see Table 3).
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It will next be necessary to extend these studies to a broader sampling of developmental pathway genes from a wider and representative sampling of nematode genomes across the full diversity of the phylum.
Total RNA was extracted from tissues of healthy adults, each sample of different developmental stages during embryogenesis, and reversely transcribed.
To generate as many gene transcripts as possible, we used a pooled sample of different developmental stages that included egg, larvae, pupa and adult.
Direct comparison of female with male samples, regardless of developmental stage, revealed means of 370 883 and 40 471 uniquely mapped H3K27me3 reads respectively on the X chromosome.
Consequently, this only allows a rough assignment of samples to developmental stages.
Figure 6 specificecimmunohistochemistryistry from tissue samples of different developmental stages (A = P1, B = P7, C = W6).
Two independent tissue samples of each developmental stage were used as biological replicates.
Sampling of the developmental series was prolonged over a 5-month period and comprised a total of 27 samples.
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