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A small sample of bone – a "bone window" – is then extracted with precision blades, to be passed on to the laboratories.
"A sample of bone (skin/hair/tissue) from a known individual related to the princes would be required, and that almost certainly means opening a second tomb in the Abbey or elsewhere.
Hematopoiesis (the production of blood cells) occurs in the bone marrow, and many types of blood disorders can be best diagnosed by analyzing a sample of bone marrow removed by a needle from the centre of the pelvic bone or the sternum (bone marrow biopsy).
A 1-g sample of bone or meat was combusted in a muffle furnace at 500 °C for 2 days for ash measurements, followed by the addition of 3 ml of nitric acid and 2 ml of perchloric acid.
Research into M. tuberculosis DNA analysis in archaeological specimens has shown that whilst the aDNA comes from a skeleton showing typical lesions, the sample of bone did not need to come from an area close to a lesion [24], [25], implying that the location of sampling may not be critical as the pathogen DNA was present in the blood stream, a theory proposed by Barnes and Thomas [26].
The number of endogenous adducts in the 312μg sample of bone marrow DNA was 13.9 adGucts/10 dG.
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Before starting treatment, she had donated samples of bone marrow and skin, so the researchers could compare her normal skin cells to cancer cells from her bone marrow.
King will carry out the tests on small samples of bone ground to a powder, in addition to the samples she has already taken.
Scientists have analysed 196 samples of bone, charcoal and shell from 40 key Neanderthal sites from Spain to Russia and concluded that this species of thick-set humans who adapted to cold climates disappeared throughout this entire region before 39,000 years ago.
Paul Mellars, an expert on Neanderthals at Cambridge University in England, said that the quality of the dates from Dr. Higham's laboratory was superb and that samples of bone re-dated by the lab's method were almost always found to be several thousand years older than previously measured.
More recent historical samples of bone and baleen from St. Lawrence Island in the Bering Sea have been used for both mtDNA and SNP analysis.
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