Approximately 5% of the sample noted that they were currently in crisis.
The CRAs in our sample noted that greater per-case reimbursement and more "credit" for CCL enrollments would be beneficial.
Some men in our sample noted that paying for testing would either discourage testing (n = 2) or decrease the frequency of testing (n = 6).
More than half of the overall sample noted that they ordered FVIII products directly from haemophilia treatment centres; the next most frequently reported ordering source was a home healthcare provider.
Whilst a large proportion of the sample noted that the phone alarms had interrupted at least one activity during the two weeks of sampling (e.g. sleeping, making dinner), most stated that they did not consider this to be a problem.
More than half (54%) of the sample noted that the ability to store a FVIII product at room temperature for a longer duration was the most important attribute compared with the ability to store the product longer in the refrigerator, indicated by only 5% of participants (Fig. 2).
Another article from the same hospital but with an earlier patient sample, noted that for one particular patient, 'the sight of her own blood often prevented a retreat into a remote and terrifying world of fantasy' (Rinzler and Shapiro, 1968: 487).
Site-specific incorporation of pAzF, as detected by MS, was greater than 95% in all samples, noting that the experimental and theoretical protein masses were in good agreement (see SI, Table S2).
To ensure our matching does not induce bias, we therefore perform a multiple imputation of matchings: of the combinatoric set of all possible matchings that use as many mice as possible, we sample 10 eligible matchings, perform Gibbs sampling of the BayesDiallel model on each, and then pool the Gibbs samples, noting that all matchings should receive equal weight a priori.
For this reason Yang et al. [ 8] suggested excluding closely related individuals from the analysis when estimating heritability from population-based samples, noting that the environmental effect shared by family members seems to be inversely related to their degree of physical proximity, so that close relatives inflate any estimate of heritability.
