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Since the single sample is substantially younger than the married sample, we are most likely to observe this in the single sample.
This correlates with the macroscopic data showing that Fe(II) sorption in the 7 days co-sorption sample is substantially lower than in the 7 days control sample (Fig. 1a).
It should be considered that the age of patients in our sample is substantially higher than usually seen in diabetes studies.
In comparison, a blood sample is substantially easier to collect, and the identification of biomarker molecules in the blood would be more widely applicable [ 18].
The study sample is substantially smaller than the base cohort, but that is largely because the research question is only clinically relevant to those with elevated HbA1c.
For a perfectly targeting instrument, the difference in means would be 0; an absolute difference of >1.0 logits indicates significant mistargeting and occurs when the amount of characteristics in the sample is substantially higher or lower than the average level of the same characteristic targeted by the items [ 24].
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Estimated mean window periods for the BED and Ax-AI assays among participants in the prospective sample were substantially longer than published window period values (330 vs. 155 days for BED, and 310 vs. 180 days for Ax-AI).
More importantly, however, we found that the correlation between replicate measurements of the same protein sample were substantially better than the correlations observed among the individuals (mean R = 0.48, range 0.38 0.60, p<0.0005) (Figure S5).
Immunoblot analysis of samples collected sequentially during the PD isolation procedure showed that the membranous sample was substantially free of contaminant proteins representative of the endoplasmic reticulum (BiP), plasma membrane (PMA2), Golgi (membrine11), and chloroplast (thylakoid P16), whilst showing a corresponding increase in the abundance of PDLP1 (Fig. 1D).
The scores in our Nicaraguan sample were substantially higher than in the Netherlands and this difference was statistically significant.
However, the age distribution of diabetics in the NHIS sample was substantially older than in this population.
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