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Sample intakes of 50, 100 and 200 mg of powdered material A were tested.
Additionally, the standard deviation of the combined data pool for the three sample intakes was estimated and a Grubbs' test for outlier screening for the three sets was carried out (Table 4).
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Notwithstanding the small initial sample intake, limits of detection as low as 0.003 0.1 ng g−1 plasma were obtained.
The within-unit homogeneity is closely correlated with the minimum sample intake.
In case the analyte content was above the method working range, the sample intake was lowered.
The minimum sample intake is the minimum amount of sample that was representative of the whole unit.
The sample intake was located in participant's breathing zone using conducive tubing attached to the device.
A quantitative analytical study of the sample intake was performed by LC MS/MS on three sets of six samples each.
Sample sizes equal to or above the minimum sample intake guarantee the validity of the certified value within its stated uncertainty.
The measurements were performed by ddPCR, using the AOB PCR assay, and the minimum sample intake for ddPCR is 4 μL.
No prior criteria were set for sample intake, sequencing, data analysis or clinical interpretation; each laboratory was entirely autonomous in choosing its preferred approach.
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