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The demographics of the sample, including age, gender living situation, are described in Table 1.
There were some missing data from the total sample including age (3.1%), gender (3.1%), country of origin (2.7%) and previous degree (10.0%).
It was the only significant predictor of subsequent neutropenic events among those available in the validation sample, including age, menopausal status, receptor status, previous radiotherapy, and first-cycle hemoglobin decrease.
The questionnaire included items to describe the clinical and demographic characteristics of the sample including age, sex, height and weight, primary reason for visiting the clinic, and current diagnosed health conditions.
Apart from CCI, CURB-65 and CRB-65, several other variables were associated with increased 1-year mortality in our sample, including age ≥65 years, nursing home residency, hemiplegia, dementia and congestive heart failure.
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A detailed summary of the sample, including ages and sexes of individuals, is provided in supplementary table S1, Supplementary Material online.
The final list of characteristics, which we considered to be important for guaranteeing versatility of the sample, included: age, gender, duration of RA, severity of RA (assessed by functional class and radiological stage), education, working status, marital status, members of family unit, and living conditions.
Details of all samples, including age, sex, and RNA quality are given in Table S1.
Patients and controls completed a questionnaire about factors that could influence volatile molecules in the breath or watery stool samples including age, physical symptoms (eg, abdominal pain or distention, bloody faeces, constipation, diarrhoea, body weight loss and abdominal tumour), history of cancer treatment, present use of anticoagulants and smoking within the previous 2 weeks.
Of the 1,928 trauma patients enrolled, 244 underwent isolated PMN blood sampling, including aged (n = 67) and young (n = 177) patients.
Further analysis for comprehensive plasma and synovial fluid miRNAs using larger number of samples including age-matched RA and OA patients with various severity and healthy controls are expected.
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