This study investigated cerium- and phosphate-based sealing treatments of PEO coated AZ31 Mg alloy samples in view of their characteristics and corrosion resistance in 0.5 M NaCl solution.
Using identification of genetic variations in prostate cancer as an example we address three crucial challenges in the field of targeted re-sequencing: Small nucleotide variation (SNV) detection in samples of formalin-fixed paraffin embedded (FFPE) tissue material, minimal amount of input sample and sampling in view of tissue heterogeneity.
To access the effectiveness of our method for selecting causal MRESS SNPs, we retrieved PubMed for all the 12,892 MRESS SNPs with proxy in GWAS datasets and defined 368 of them with at least one query result as positive samples (In view of the foreseeable importance of the MRESS region, we removed SNPs that have been reported to be in MRESS to suppress the priori bias).
The sampling strategy was largely a convenience sample 4 in view of the difficulties in bringing busy GI clinicians and nurses together for UK-wide focus groups.
Other researchers comparing culture with a gonorrhoea NAATs using endocervical samples have also performed the culture sample first, in view of the reduced sensitivity of culture.
The results of this study should be validated with a larger sample size, in view of the rare outcome of cardiac arrest within 72 hours or death.
22 The limitation of this research was that we used a smaller sample size in view of the high cost of HbA1c, which affected our analysis when we stratified further in terms of diabetes type.
If filtering or thresholding is not selected, the user is alerted to the fact that filtering or thresholding is possible but only in applicable cases, e.g. if the scale maximum has changed between views or if the replicate values for a given sample in a view exhibit high variation.
Nevertheless, the current findings require replication in independent samples, especially in view of the high rate of ASD diagnosis in our sample relative to other samples (20).
Whatever residual effects there are probably do not amount to much more than statistical noise from a small sample, in my view.
