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A small number of taxa skews the content of the categories since class data are calculated as a proportion of the total number of taxa and 10 is suggested here as a minimum sample for this type of study.
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However, this might be seen to be consistent with the 'spirit' of consent, or justified by the need for samples for this type of research.
However, plasma was not available for all time points during treatment, highlighting the difficulties in the collection of clinical samples for this type of study; however, baseline pretreatment plasma samples were collected from all patients undergoing chemotherapy.
Larger sample sizes for this type of research question are important given their observational study designs.
In a review of studies that recommended minimum sample sizes for this type of analysis, 400 was the upper limit of the recommendations (28).
All hospitals (clusters) had sufficient patients (n>30) according to previously recommended sample sizes for this type of model to reduce bias.
The strengths of the study include the relatively large sample size for this type of study, its longitudinal design and the standardisation of assessment methods through training and use of standard operating procedures.
Although this would result in a smaller sample size for this type of analysis, resulting in reduced statistical power, the authors felt that excluding recent records (less than 6 months) enabled a more reliable picture of the long term care resident at this home.
There were minimal inflammatory infiltrates in the periphery of the sample, considered normal for this type of tissue.
The large sample reference distribution for this type of test is usually considered to be a 50% mixture of a point of mass at zero and a χ (1) (Self and Liang 1987).
In terms of the composition of the sample for the type of employment, we note that half as many females as males are entrepreneurs.
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