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Our findings indicate that when data from well-correlated biological replicates are included, 2-3 million fragments per sample enable a significant number of genes differentially expressed by 2-fold or more to be identified with high statistical significance.
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Meanwhile, the transcriptomic analysis of the metastatic sample enabled a molecular subclassification as Basal-Like 2 with EGFR mRNA overexpression [ 1, 2].
It is noted that a limitation of the evaluation methodology is that the sample frame was relatively small, but that the small sample enabled a thorough, in-depth investigation of the selected schools using a mixed-methods approach.
This national survey draws on a much larger and more representative sample, enabling a better understanding of confidence levels and current practice among trainee doctors in the provision of care for people with diabetes.
How does the approach to sampling enable a valid capture of the chosen population?
The determination the activity of alkaline phosphatase in serum samples enabled a quantification range of 0.3 mU/L–1 U/L with a detection limit of 0.1 mU/L.
A total of 26 breeds included 7 or more samples, enabling a thorough identification of single breed CNVs, i.e. CNVs present in one breed exclusively.
Several outlier loci that could underlie adaptive differences were discovered, and the sampling enabled a comparison of outliers across space as well as time.
In full 3D imaging with a small (point or line) sensor, where signals are taken all around the sample, the full k-space is sampled, enabling a reconstruction with uniform resolution [ 22].
Qualitative research undertaken using purposive sampling enables a wide range of experiences and opinions to emerge, but further quantitative work, particularly among providers, is needed to determine the true prevalence of our findings.
In the present study, a switch was made from analysing the samples with IF (n = 327) to IC (n = 74), a method with growing acceptance at the time, and with the use of published standards for handling of the samples, enabling a more strict morphological evaluation [ 18, 19].
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