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At higher current densities a self-localizing mechanism concentrates the ionic current to a smaller, spot-like area that moves continuously along the sample consuming steadily the whole metal thickness under the spot and thus forming a porous anodic film of highly self-ordered morphology, without physical imperfections.
These techniques are not sample consuming techniques and allow the opportunity for further analysis to be undertaken with other techniques.
For example, tissue, cell, age or stage-specific libraries could be rapidly constructed and tested without the need for tedious and sample consuming normalization steps.
The sheer number of members in the different HERV families [ 26] makes it a prohibitively expensive and sample consuming to determine expression patterns of more than a few elements within the different HERV families.
Therefore, although moving the population to this diet may be difficult, there are already individuals within the UK (around 6% of the NDNS sample) consuming a similar, achievable diet.
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But this kind of model is difficult to be as the large-scale screening method because it demands a large number of experimental animals and the test samples, consuming large amounts of time and manpower.
However, the conventional assay using a 96-well microtitration plate is time- and sample-consuming, and therefore is not suitable for rapid diagnosis.
The CIPers universal primer sites can be formatted to fit any amplification method, e.g. RCA [12], [13], emulsion PCR [34], SPIA [35] LAMP [36] and SMAP 2 [37]; universal adaptor ligation, a tedious and sample-consuming procedure [38], is therefore optional.
However, these methods are time- and sample-consuming because of their one-gene-at-a-time approach.
Our data support future use of the highly sensitive, low sample-consuming PLA for detection of protein:protein complexes in plasma.
However, Markov Blanket based method is sample-consuming and the greedy searching strategy in Markov Blanket method is not suitable for detecting some interaction models with no independent main effects for each disease locus.
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