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end{aligned} (4.2) Figure 11 Reduction of sample complexity for virtual tensile strength tests.
To reduce sample complexity for data-dependent screening for PTMs, histones were purified from tissue.
Each sample lane was cut into four slices to reduce sample complexity for subsequent analysis.
Obozinski et al. (2008) found that for k regressions, under certain conditions, the sample complexity for L1/ L2, is up to k times smaller than the lasso sample complexity, with weak assumptions of shared support.
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The lowered sample complexity of our Cys-peptidome could be a factor of importance for the improved performance.
In the latter case, we provide both algorithms and sample complexity results for the class of scoring functions, and further validate the approach empirically.
The first 10 fractions from SCX were analyzed using an 88 min gradient and the next 11 fractions were analyzed using a 55 min gradient, since the first 10 fractions had greater sample complexity, allowing for more peptide identifications (data not shown).
Such stepwise elution is beneficial for reducing sample complexity and thus for increasing the probability of phosphopeptide identification.
With this procedure small volume samples could be rapidly desalted, reduced in sample complexity and enriched for AMPs and allowed the processing of multiple samples in parallel for nanoUPLC-MSE analysis.
Coupling immunoaffinity depletion with strong cation exchange (SCX) fractionation further reduces sample complexity, and allowed for the in-depth analysis of the CSF proteomes.
By this approach, we were able to tremendously reduce the sample complexity by enriching for the TG2-modified peptides and thereby facilitating identification of individual peptides.
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