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Registration-focused trials are limited by the small and select sample chosen for study participation and design constraints.
Here's a sample chosen at random: "... heroes are often wreathed in shadows, marked by Hades great eater of warriors, Eduardo as well as others, even though in those days journalists were falling like flies, in Croatia at least, or later on around besieged Sarajevo – in central Bosnia, between Vitez and Travnik, they made themselves much scarcer...".
As Goldwasser - clearly the analytical half of the band - points out, it was unfortunate that the 30-second sample chosen by iTunes just happened to be the 30 seconds that mentions heroin and cocaine and includes swearing, and so out of context it might sound like "the most evil music in the world".
The sample chosen (N ~ 1 500) was based on quotas controlled by telephone.
Also, the analysis shows that the type of sample chosen has no significant effect on the developed methods.
The accuracy of the NMR method is heavily dependent on the accuracy of the weight taken for reference compound as well as for the sample chosen.
Similar(21)
Almost two thirds of the participant sample chose the device they perceived the least secure as their preference.
Each sample chooses a single path, which leads to a feasibility problem.
Sixty-five percent of our sample chose either hospital or care home as their least preferred place.
A third of the cross-sectional sample chose something other than to recommend taking the medication in the baseline condition.
When the delayed payment was the smallest ($10.75), only 23% of the overall sample chose the delayed payment.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com