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As regards to the second challenge, exhaustive sequencing of a human peripheral blood sample cannot capture full TCR repertoire diversity [ 9].
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A random sample cannot be captured by people with intense interests volunteering themselves.
This fine-tuning exercise becomes extremely time consuming in a high throughput setting, especially as expected differences in the patterns of data between samples cannot be captured by a single parameter set.
4. Full sample view: Since the individual tile/panel based visualization cannot capture large scale quality pattern across the full sample assay, NGSQC provides full sample view of several quality control measures derived from individual tiles.
However, it cannot capture the nonlinear relationships among samples.
Consequently alternative and less advanced approaches are often applied that cannot capture the full structural complexity of a 3D sample.
Whilst the model output might be a good fit for the sample, it is known a-priori that the sample cannot represent reality accurately as it is too dynamic to be captured within a week of sampling.
Even sample splitting by observed covariates in standard models (e.g., OLS, Poisson and logistic regression) cannot capture differential responses which are due to unobserved characteristics [42].
PS has been very effective at capturing the parent average component of the EBV, but cannot capture variation in the proportion of genome shared by pairs of relatives due to Mendelian sampling in the absence of an individual's own phenotypic record or those of its descendants [ 2, 3].
You cannot "capture" deserts.
They cannot capture him.
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