This analysis showed that the vast majority of the known SNVs present in a single sample can be reliably detected in the pools, with the number of false negatives ranging from 1 to 7 and the number of false positives ranging from 1 to 14 (Table 3).
We will show below, however, that in both simulations and real tumor samples, MixHMM can reliably detect the CNV states up to seven copies in a sample mixed with up to 0.6 proportion of normal cells.
These data show that instrumented indentation of fully immersed samples can be reliably applied for materials spanning several orders of magnitude in stiffness (E=kPa GPa).
Therefore, miRNA from small tissue samples can be reliably assayed.
The objective of this study was to determine whether different types of voice samples affect rater reliability and which type of sample can be rated most reliably, with particular reference to two types of connected speech passage reading and conversational speech.
Internet-based surveys can be an efficient way to recruit larger numbers of participants, and our results demonstrate that these participants can reliably provide biomarker samples.
This is useful to understand how variable the ASHA's own procedure times can be and with sufficient samples (of risk assessment procedures), we can reliably estimate how long an ASHA can take and how much training is needed until she is proficient to use the CDS tool (which may be shown by a narrow confidence interval).
A recent simulation study (Antao et al. 2010) suggested that both single-sample and temporal-method estimators of Ne can reliably detect moderate to severe population declines.
The PCR assay can reliably be performed on FFPE samples and has a faster turnaround time than current IDH mutation detection algorithms.
It should be noted that even 'low frequency' receptors may represent amplified clones, as sample size limits the lowest observable TcR frequency we can reliably see.
