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Despite small sample and often poorly defined patient populations sizes in most studies, randomised, controlled trials support the efficacy and tolerability of Vitex agnus-castus extracts in the treatment of premenstrual syndrome, premenstrual dysphoric disorder, premenstrual mastodynia and mastalgia accompanied by latent hyperprolactinaemia and of fibrocystic mastopathy.
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Or else they are dimly aware of a restless and protean figure who amid the ripening of a career sampled, and often mastered, other genres and styles a man of many talents and a few excesses.
While her records include electronic elements, samples and often lavish instrumentation - Let Me Back, her debut single, recalls Young-Holt Unlimited's Soulful Strut; Box of Secrets is a vaudevillian big band extravaganza; Over is a meticulously arranged break-up song with Lauryn Hill-like husky vocal flourishes - the key for Davidson is in the writing.
Or else they are dimly aware of a restless and protean figure who amid the ripening of a career sampled, and often mastered, other genres and styles — a man of many talents and a few excesses.
However, the more complex theories are likewise more challenging to test, requiring larger samples, and often more nuanced experimental designs, as well as detailed data on many aspects of household and community behavior and outcomes.
Thirdly, the studies sampled and often combined data from different regions of the brain.
Studies aiming to precisely estimate the prevalence of disease usually require large samples and often use postal questionnaires.
In addition, EM imaging can only be performed on fixed samples and often requires harsh sample preparation techniques that can disrupt native protein structures.
This fact limits the identification of molecular signatures in high-background samples and often relegates both single-molecule and bulk spectroscopies to rigorous exclusion of unwanted absorbers to minimize interference.
Population studies based on relatively small samples, and often with a low response rate, report that 4 – 49% of the general public have experienced AEs related to their own or family members´ care [ 9- 13].
However, interpretation of these findings is limited by small sample sizes and often heterogeneous cellular composition of the samples investigated.
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