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In some discrimination methods, M-distance limits of 10 15 for maximum variance have been reported for classifying samples but threshold values vary according to the type of sample and application [44].
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The general idea of iterative timing recovery scheme is to improve the timing estimation accuracy by multiple exploiting the timing information provided by a set of samples and application of this estimation to regenerate a new set of samples that iteratively approaches to the local maximum of the likelihood function.
An IDF provides general information about an experiment including the protocols used, while an SDRF describes samples and application of protocols, and provides links to data files associated with the samples.
This requires close collaboration between the human and veterinary public health sectors to ensure timely detection of cases, identification of plausible sources and standardised environmental sampling, and application of public health and veterinary preventive measures.
Mass spectrometry (MS) has emerged as a method to quantitatively analyze proteins in biological samples, and application of MS to patient-derived tissue could have a large, positive impact on patient stratification and targeted cancer therapeutics [ 8- 12].
However, analyses based on denser sampling and application of the new generation of powerful DNA sequence analysis has the potential of producing a very detailed phylogeographic map of the region, promising a detailed picture of the first steps in dog origins.
First, despite national sample frames and application of sample weights, the aggregated results from some surveys may not adequately reflect the national average.
Consequently, extraction methodologies must be optimized for each sample type and application [ 18].
Additional file 1 provides a step-by-step description on how to install Cytoscape, KeyPathwayMiner, and how to analyze the dataset (a sample file and application case is provided with the additional material).
To this end, we conducted a prospective cohort study involving separate samples for instrument development (derivation sample) and clinical application (validation sample).
The major results of the following study are the mean average performances of the sample and the application of the progression regression law on performance.
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