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On the other hand, the same single dose of AdPSAE1 injected into the RT4 xenograft tumors failed to result in significant growth inhibition, as compared to the untreated RT4 tumor group).
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When the rats were treated with the same antidiarrhoeal single dose of S. boulardii, no increase in citrulline level was observed.
We assume that in the initial campaign the percentage of the population covered at each of the three doses is the same and that after 5, 10, and 15 years, the same percentage of the population (all ages), but not necessarily the same individuals, receives a single dose.
Pretreatment of these same subjects with a single dose of acarbose markedly reduced postprandial hyperglycemia and associated endothelial dysfunction after the ensuing meal.
A trial comparing azithromycin with tetracycline, both given for the same effective duration (eg single dose azithromycin versus three to four days of tetracycline) would be interesting, since azithromycin has so far only been compared with erythromycin and ciprofloxacin given for shorter durations.
For the same single-fraction tumor dose delivered, the total number of MUs for IMRT is much greater than for a conventional treatment.
However, mice treated with a single dose of the same concentration of ch-mAbs showed considerable weight loss (up to 10%) and provided only 80% protection.
In contrast, mice treated with a single dose of the same concentration showed a loss in body weight of up to 15% (Fig. 3C and 3D) and provided only moderate protection (60 70%) against H5N1 viruses (Fig. 3A and 3B).
In treated mice, this trend is reversed with negative values of regrowth (indicating mean tumour destruction) of −58.8% and −30.2% in the same sites, consistent with the modest, single dose of PDT applied here.
The findings are also consistent with recent estimates of vaccine effectiveness derived in a smaller test negative case-control study among children under 10 years of age in New Brunswick, Canada (28 cases (none vaccinated); 63 controls (24 vaccinated)) given a single dose of the same product (100%, 79.5% to 100%).
Rituximab dosed at the same single chain concentration showed variable induction of apoptosis in CD20+ cell lines with Raji cells responding better than SU-DHL-7 cells.
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