Exact(30)
The same severity of genotoxicity causes more severe DNA damage in cancer cells than in normal cells, thus eliciting cancer cell-specific killing, because normal cells have intact DNA damage response and intact DNA repair mechanism and thus can arrest proliferation for more efficient DNA repair and to avoid damage by the drug.
Accordingly, it might be speculated that a hypothermia-associated improvement of cellular and organ function might deteriorate after rewarming and ultimately result in the same severity of cellular and organ dysfunction as maintenance of normothermia.
We matched 176 patients aged 90 years old with patients between 80 and 89 years old hospitalized in the same center and the same severity of illness at admission (Table 57).
Of note, the cut-off values of LI used here were based on our previous study in RCVS patients using TCCS[7] and should not be translated to the same severity of vasopasm in SAH based on studies using transcranial Doppler (TCD)[22].
Among patients with an APACHE III score of 60, patients with workload/staffing ratio of always <40 during the ICU stay were twice as likely to survive to hospital discharge (odds ratio 2.28, 95% CI 1.07 4.80) than other patients with same severity of illness but receiving higher workload/staffing ratio (ie. sometimes or always above 40).
Compared with control patients, with the same severity of illness at ICU admission, case patients were more often admitted for unscheduled surgery, had similar intensity of treatment (invasive and noninvasive ventilation, and use of vasopressive therapy), but had a lower use of arterial catheter monitoring (37/176, 21%% vs. 53/176, 30%%, p = 0.04) or RRT (5/176, 2.8 % vs. 14/176, 8%%, p = 0.05).
Similar(30)
In addition, although the patients included in the present study were all diagnosed with the same severity level of AD, the full extent of the pathology cannot be established with certainty in any subject and the degeneration might have differentially involved the regions of the BFCS, leading to the cancellation of specific temporal distortion when analysing the average behavioral performance.
As patients with the same diagnosis does not always mean the same severity, the severity of disease score is mainly based on the prototypes for severity of disease as described in the guideline.
In addition, of same severity grading, swelling in lower extremity reacted to treatment more favorably than that of upper extremity.
For a given number of patients treated of the same severity level (i.e. fixed k and s), the higher the waiting time, the lower the hospital's utility.
C4-deficient KRN/NOD mice develop arthritis of the same severity as do wild-type mice, whereas animals deficient in factor B of the alternative complement pathway develop attenuated disease or no arthritis at all [ 16, 17].
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