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The same rate of chromosome loss has been observed in Sc. pombe (Bodi, Gysler-Junker and Kohli 1991).
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We found the same rate of discordant X-chromosome inactivation pattern and/or BRAF mutational status (28.6%, 2/7 cases) in tumors whether there was bilateral or unilateral lobe involvement (Tables 2 and 3).
Thus, even with the same rate of mutation, recessive mutations on the X chromosome are subject to more rounds of selection than mutations in the autosomes, and consequently should have a better chance to become fixed.
It also allows ranking of compounds with the same or similar mechanism of action based on their effect on the rate of chromosome loss.
The rate of chromosome number abnormality in porcine sperm was found to be 6.25% (70/1120).
Diploid Saccharomyes cerevisae strains lacking the RAD52 gene required for homologous recombination have a very high rate of chromosome loss.
Likewise, the rate of chromosome loss observed in nod is similar to the rate at which these chromosomes fail to associate with the main chromosome mass.
For example, the X/2L relative euchromatic recombination rate is 1.22 for D. melanogaster (data from Flybase.org) while the same rate for the homologous chromosomes of D. pseudoobscura (X/4) is 1.94 [ 63].
These observations may explain the differences in rates of chromosome reshuffling during the evolution of different lineages and among chromosome arms in the same lineage [ 27, 28, 40].
By using a multiply marked supernumerary chromosome III as an indicator, we isolated mutants of Saccharomyces cerevisiae that display increased rates of chromosome loss.
They found one, and mapped it to the same stretch of chromosome 8 that their other experiments had identified.
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