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First, we included the same number of studies per disorder (i.e. seven); if a disorder had been studied in more than seven studies, then the studies included in our investigation were selected randomly.
Data on discontinuations because of adverse effects were available for the same number of studies and subjects for placebo comparisons but for 13 studies using active comparators (2352 participants for agomelatine; 2207 for comparator).
During the debates, Johnson pointed out there are about the same number of studies linking breast cancer to passive smoking as there were linking lung cancer to SHS in 1986, when the Surgeon General concluded that passive smoking caused lung cancer.
For the five reviews with widened CIs, two had the same number of studies but had re-extracted the data from their original studies and in the other three reviews the updated meta-analysis led to only a small change in the precision (ratio range 1.04 1.11).
We thus repeated the VBM meta-analysis for each disorder 100 times, including the same number of studies randomly sampled with replacement (bootstrap), and calculated the difference between the median degree of the lesion and non-lesion voxels in each of the bootstrapped maps.
To avoid the disorder general maps being biased by the most frequently studied disorders, which also tended to be studied in the largest primary samples, we included the same number of studies (n = 7) per disorder, by randomly sampling a subset of seven primary studies of those disorders, which had been the focus of more than seven published VBM studies.
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Since more species of pinacitids have been described, the analysis is performed by first merging the data of the phylogenetically closest species of the pinacitid lineage in order to obtain the same number of studied evolutionary levels or steps for both families.
The department estimated that the new system would see about the same number of vocational study loans, up from 115,000 in 2016 to an estimated 159,000 in 2020.
An implication of this is that multiple small new studies can, in aggregate, be weighted more than a single large study containing the same number of subjects as the smaller studies in total in an updated meta-analysis; this has important implications for design of future studies.
The study examined approximately the same number of patients as our study reported anti-enolase AAbs in 67% of the AMD patients, which are similar to our findings [ 17].
The cumulative number of cases in the Australian registry accounts for approximately the same number of cases described in studies from elsewhere.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com