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To investigate whether the translocation of GST-C utilises the same mechanism of cell entry as its parent molecule, the uptake of GST-C-OG was initially compared by confocal laser scanning microscopy.
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In order to determine whether endogenous SRSF1 translational targets responded to the same mechanism of translational activation we treated cells transiently expressing SRSF1 (or control cells) with a specific inhibitor of the mTOR kinase, PP242 (Dowling et al. 2010) and then measured polysomal to subpolysomal ratios of a subset of selected SRSF1 translational targets.
The studies presented here identified the same mechanism of TRAIL resistance in the two cell types.
It is possible that the same mechanism of BimEL inhibition operates in HTLV-1-infected cells or ATL cell lines.
In addition, annexin II inhibitors prevent PCa cells adhesion to osteoblasts and endothelial cells, thus strongly suggesting that PCa cells employ the same mechanisms of hematopoietic stem cells to gain access to the bone niche [ 146].
GNPs might not have all the same mechanisms of action and may induce distinct repair kinetics across different cell lines.
The same mechanism allows cells of the osteoblastic line to hold HSC within bone marrow niches formed by both MMSCs and osteoblasts [ 112].
Third, there is an enhancement of L-PAM cell killing by MISO over and above these two competing processes which is probably a result of the same mechanism by which cells in vitro are sensitized to L-PAM by pre-exposure to MISO under hypoxic conditions.
Although cell proliferation is one mechanism of increasing cell numbers, a second mechanism of cell specification can also achieve the same effect.
The same caspase activity probes allowed to shed light on the mechanism of cell-to-cell variability upon TRAIL induction.
Each depends on the same mechanism, the interaction of skin cells called fibroblasts with the collagen they produce.
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