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These genes are possibly expressed in different tissues and have different degrees of interaction for the same loci as well.
A more recent GWAS of secondary tooth eruption identified two of the same loci as well as two others containing the genes ADK and CACNA1S/ TMEM9 (7).
This includes performing duplicate reactions for the same sample or through internal validation by having overlapping amplicons covering the same loci (as is the case in the newer TruSight™ version of the TSACP panel that was released after this study was concluded).
The PowerPlex® ESX 17 System amplifies the same loci as the PowerPlex® ESX 16 System, but with the addition of a primer pair for the SE33 locus.
The PowerPlex® ESI 17 System amplifies the same loci as the PowerPlex® ESI 16 System, but with the addition of a primer pair for the SE33 locus.
Of interest, MSG and SR highly cooperate in the pathway of chromosomal losses that is associated with the so-called LOH pathway since it leads to frequent chromosomal losses of the same loci as those identified by LOH in CRCs, e.g. 17p, 18 and others that contain tumor suppressor genes.
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In Xcv 85 10, IS 1595 is located at the same locus, as well as xopD and two genes coding hypothetical proteins.
Secondly, we used the CLEANUP program [ 62, 63] to detect and eliminate duplicated sequences and to facilitate the identification of different alleles of the same locus, as well as loci shared among species.
Cytogenetic interpretation can be particularly difficult for complex karyotypes, cryptic translocations such as the TEL-AML1 translocation, and multiple chromosomal rearrangements that have been identified for the same locus, as is the case for chromosomal abnormalities involving the MLL gene.
Since the catalogue often contains multiple or alternative gene models at the same locus as well as duplicate or overlapping features of the same type within the same gene model, a C++ program was written by CM to remove multiple gene models in order to avoid an overrepresentation of these loci in the analysis.
Because only one isoform (the longest) per Locus was considered, the degree of redundancy may be attributable mostly to the inherent duplication of the hexaploid oat genome, and suggests that homeologous genes may be assembled within the same Locus, as well as in different Loci, depending on how divergent the homeologs are.
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