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Two, alternative drug costs to those observed were used by substituting them with the cost of the least costly drug with the same active principle as that dispensed, as well as with the least costly drug among those available in Italian market.
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Albiglutide (formulated in 10 mmol/l sodium phosphate, 4.2% trehalose, 2.8% mannitol, 0.01% polysorbate-80) and placebo (same formulation without active principle) were administered in the physician's office over the course of 16 weeks.
Two different TEOS mixtures were used for the two lithotypes (a commercial mixture for GL, a mixture prepared in the laboratory for GS), maintaining the same catalyst (1 wt% DBTL) and the same ratio between the active principle and the solvent, so that the only parameter to change was the solvent type.
This means that the active (principle) is at the same time active and passive, being affected in the course of its activity (as principle).
In 1908, Ikeda who was a professor of physical chemistry in University of Tokyo began to identify the active principle in kombu and identified the principle in the same year [ 1].
But for him love was a revolution-weapon: the active principle, as strong as electro-magnetism and, he surmised, the same force, by which the universe worked and by which men would be perfected.
Salidroside was isolated as an active principle.
Toxicity of the pure active principles follows the same order of the photostability.
Same principle, different activity.
Both PALM and STORM methods use the same underlying principle to reduce the number of active fluorophores.
Same general principle as a microwave oven.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com