Sentence examples for same aberration from inspiring English sources
A drug, Herceptin, which greatly helps breast cancer patients with too many ERBB2 genes, might also help colon cancer patients with the same aberration.
Two pairs of patients carried the same aberration and one patient carried 3 changes, leaving 11 unique copy number changes identified in a total of 11 patients.
Amp14 was detected in 14 patients (12%) with 4 17% of the lymphocytes having the same aberration in seven of those patients (50%).
A recurrent alteration was considered when two samples with CHD harbored the same aberration (hyper- or hypo-methylation) at the same CpG.
Since our goal was to find duplications and deletions that were de novo, a criterion for selection of CNVs for further analysis was that the child have the same aberration with each parent as reference.
Abnormalities were considered clonal if ⩾2 metaphases had the same aberration in the case of a structural abnormality or an extra chromosome, or if ⩾3 metaphases shared the same abnormality in the case of a monosomy.
The same aberrations were shown for laminin staining, a marker of the basal membrane.
Indeed, the same aberrations in cortical cytoarchitecture, hippocampal disturbances and spontaneous epilepsy that have been detected in RGC-targeted Tsc2 mutants were observed in RGC-targeted Tsc1 mutant mice.
Interestingly, pseudodiploid and aneuploid fractions carried the same aberrations as defined by identical chromosomal breakpoints, suggesting that evolution towards aneuploidy is a late event in GBM development.
As shown in Figure 2, the sample from the mucosal part of #S3 showed 4p-, 4q-, 8q+, 9p-, 13q+, 18q-, 18q-, 20q+ and Y-, while the sample from the invasive part of #S3 inherited the same aberrations from the mucosal part, showed additional aberrations (2q-, 7p+, 8p-, 14q+, 14q+ and 20q+) and lost 4p- and 22q+.
Nowadays, the presence of specific genetic aberrations is progressively used for classification and treatment stratification, because acute leukemias with the same oncogenetic aberration generally form a clinically and diagnostically homogenous disease entity with comparable prognosis.
