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So companies make a business decision: would obtaining F.D.A. approval increase sales enough to justify the expense of additional drug trials?
The book was not an immediate best-seller, but critical acclaim and steady word-of-mouth recommendations eventually boosted sales enough for Herbert to become a full-time writer and embark on a sequel.
The drug makers seem unable, he said, to raise prices and reduce costs of production and sales enough to keep profits rising during fallow periods when important new drugs are scarce.
The old, old, old-school rappers Beastie Boys received positive reviews for their latest release, "Hot Sauce Committee Part 2," and with 128,000 sales, enough for them to land in second place, but a far cry from the 360,000 sales that their last proper hip-hop album, "To the 5 Boroughs," enjoyed at its release in 2004.
Specifically, the questions concern claims being made by CNN and ABC News that a joint venture would enable them to marry their resources, cut redundancies and increase ad sales enough to generate more than $200 million in additional profits a year for the combined company.
Billboard estimated that about 15,000 copies of the album were sold through the discount, which, had they counted, would push Mr. Ocean to 69,000 sales — enough to beat "Kidz Bop" for No. 3. Also on the chart this week, Justin Bieber's "Believe" (RBMG/Island) fell two spots to No. 5 with 45,000, and a 15-year-old album, Phil Collins's "Hits," landed at No. 6.
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Radio industry executives estimate that WEVD, which is marginally profitable, could bring $80 million to $90 million in a sale, enough to keep The Forward running for at least four more decades.
And the school hopes to make big profit, more than $100 million, on the sale, enough to create an endowment and build a new school.
And that leads to making far less than we should, not asking for the sale enough, doubting ourselves, and playing the comparison game in our minds.
This side business, Shearwell Data, generates $1.2 million in sales annually — enough to keep his farm solvent, but not enough to make him rich.
The bitter news of declining marmalade sales is enough to put any right-thinking Brit right off their breakfast.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com