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Vaccine safety was evaluated using active and passive follow-up.
Safety was evaluated using side effect or adverse event data obtained from the Case Report Forms (CRF).
Efficacy was evaluated using inflammatory and noninflammatory lesion counts, and safety was evaluated using scores for facial erythema, peeling, burning, dryness, and pruritus.
Safety was evaluated using Common Terminology Criteria for Adverse Events v3.0, by compiling adverse events in the treatment group and comparing standard and investigational treatment groups in terms of the incidence of adverse events.
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Usefulness of the above social media platforms for safety surveillance was evaluated using two examples of drug adverse event associations that have previously been flagged as potential safety signals: (1) rosiglitazone and cardiovascular events (i.e. stroke and myocardial infarction); and (2) HPV vaccine and infertility.
The safety profile was evaluated using red cell haemolysis and in vitro cytotoxicity assays.
In vitro safety profile was evaluated using red cell hemolysis and in vitro cytotoxicity assays.
The safety profile was evaluated using red cell haemolysis and in vitro cytotoxicity assays and the in vitro leishmanicidal activity was evaluated using a MTT colorimetric assay.
The safety of J147 was evaluated using acute toxicity, the hERG assay, CYP450 3assaysand and the Ames test, all of which were negative.
FLU-loaded MEs improved the FLU safety profile that was evaluated using red cell haemolysis and in vitro cytotoxicity assays with J-774 mouse macrophages.
Safety-related information was evaluated using descriptive statistics.
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