Sentence examples for safety selectivity from inspiring English sources

The success of mAb-based therapies is based on their safety, selectivity, diversity, solubility, tolerability, stability, and long circulating half-life.

However, the implementation of this reaction still faces major hurdles including safety, selectivity and productivity of the reaction.

With regard to safety, selectivity, and up-scaling a flow-chemistry procedure for the TRF reaction has been developed.

Despite intensive research carried out by academia and industry over the past decades, the liquid phase direct hydrogen peroxide synthesis still faces a lot of challenges including safety, selectivity and productivity of the reaction.

Thus selective Bcl-2 SMIs demonstrate a distinct advantage in drug safety, although selectivity can also lead to resistance, as was seen in the case of ABT-263 and ABT-737.

Besides the development of different reactor concepts, one attempt to address the issues concerning safety, activity, selectivity and cost, is the search of alternative solvents.

The results of ex vivo experiments with different tissues as well as in vivo experiments with blood vessels are presented that prove the efficacy, safety and selectivity of the developed HIFU transducers and methods.

The oncolytic activity and efficacy of VSV as a cancer therapy are well demonstrated in mouse models, and the important remaining issues are the safety and selectivity [121].

It should be noted that there are some challenges and risks for miRNA-based therapy like safety, delivery, and selectivity [ 68].

Furthermore, a better control of polymer degradation and release properties in accordance with the skin environment would improve the safety and the selectivity of drug release.

As summarized herein, a final optimization by synthesis and screening yielded MW150 that has improved HLM stability (T1/2 > 60 min) and oral bioavailability (>50%) as well as an incrementally improved p38αMAPK inhibition activity with retention of target selectivity, safety, and brain penetrance.