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$6$$)Reducing safety ratios, which measure capability to withstand expected impact.
The results indicated that risk, measured by the system probability of failure, is not a linear function of safety ratios.
All three safety ratios in question were positively correlated, with bearing capacity being subjected to higher degree of uncertainty.
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The result is expressed as a projected environmental safety ratio (PEC/PNEC = PESR).
In addition, the proposed safety ratio only considered bridges with a single pier against flood hazard.
A very high safety ratio and an absence of interaction with other mechanisms involved in blood pressure regulation, together with initial evidence of high tolerability and efficacy in hypertensive patients, indicate Rostafuroxin as the first example of a new class of antihypertensive agents designed to antagonize adducin and EO-hypertensive mechanisms.
The biomonitoring data indicate margins of safety (ratio of BE value to biomarker concentration) of approximately 200 at the central tendency and 50 at the extremes in the general population.
In early 2005 the UK Medicines and Healthcare products Regulatory Agency announced gradual withdrawal of co-proxamol because of its adverse benefit to safety ratio, especially its use for intentional and accidental fatal poisoning.
The profile of a drug is best described by its efficacy-to-safety ratio, but this ratio may vary as a function of the dose used.
Campbell and colleagues [ 31] reported serious injuries that included fractures, hospitalisation and injuries requiring stitches but there was no evidence at the 5% level of significance of an effect for either exercise and Vitamin D (risk ratio =0.98, 95% CI 0.25 to 3.84) or exercise, Vitamin D and home safety (risk ratio =2.7, 95% CI 0.89 to 8.17) versus control.
Although the proposed safety frequency ratio is consistent with a field observation, the parameters used in this study are from Taiwan only.
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