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This paper presents an approach to provide indicators for maintainability and safety prediction at early stage of design.
This research recommends a model which utilizes spatial considerations for horizontal curve safety prediction in addition to current Highway Safety Manual prediction capabilities using individual curve geometric features.
Extracted data are integrated with internal and external data sources for target evaluation, safety prediction and data analysis using computational approaches.
More and more data have accumulated over recent years in regard to long-term efficacy and safety, prediction of response, and the relevance of extrarheumatic manifestations such as uveitis, psoriasis, and inflammatory bowel disease for treatment decisions with TNF blockers.
This curation project expanded the number and coverage of chemical disease interactions in public CTD, allowing a better representation of the drug-induced events for the four physiological systems central to Pfizer drug safety prediction: cardiovascular, neurological, renal and hepatic toxicity.
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Effects on efflux systems could result in unanticipated accumulation of toxicants in humans and confound safety predictions of seemingly innocuous chemicals.
If so, they write, the result could be unanticipated accumulation of toxicants that would confound safety predictions of seemingly harmless chemicals.
The most salient outcome is that much more research on cutaneous XME is needed for solid metabolism-dependent efficacy and safety predictions, and the cutaneous metabolism comparisons have to be viewed with caution.
The development costs per marketed compound are becoming prohibitively expensive, and any assays that have the potential to reduce these costs, via more accurate and/or earlier safety predictions, are worth investigating (Mirams and Noble, 2011).
A safety-prediction as well as safety-evaluation approach of NMs is an essential prerequisite for maintaining the well-being of the general public.
The authors have proposed the solution to solve the context-aware safety hazard prediction using the concept of field theory.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com