Sentence examples for safety expansion from inspiring English sources

No DLTs occurred in any dose-escalation cohort or the safety expansion cohort.

10 In the safety expansion portion of the trial (n = 66), buparlisib was well tolerated with a minority of patients experiencing Grade 3/4 adverse events (AE).

Other than patients with GBM, who could enrol in the safety expansion cohort or in the erlotinib combination cohort, patients with central nervous system disease were excluded.

Six monotherapy patients died during the study or within 30 days after the last dose (one in the 2 mg kg 1 cohort, two in the 10 mg kg 1 cohort and three in the safety expansion cohort).

The planned enrollment for phase 1 was up to 36 evaluable patients, including up to 27 evaluable patients in three dose cohorts during dose escalation and approximately 9 evaluable patients in a safety expansion cohort at the MTD/RP2D.

The ficlatuzumab 20 mg kg 1 dose-escalation cohort (n=4) and the safety expansion cohort (n=11) were combined for all subsequent analyses of ficlatuzumab at the RP2D as monotherapy.

Machiavelli had stated with unblinking realism how, in fact, tyrants behave, and, far from criticizing their conduct or distinguishing between the just prince who rules by law and the tyrant whose laws are in his own breast, he considers that the successful ruler has to be beyond morality, since the safety and expansion of the state are the supreme objective.

Either way, less labor is the result of the safety net expansion in the sense that keeping the safety net constant would have resulted in a time path for labor that was above its actual path.

Appendix 1 contains the derivation of equation (6), which can be used to understand the size of the uncertainty or risk aversion impulse that would be needed to rationalize a safety net expansion like the one experienced since 2007.

Adequate parenting related to these dimensions may require that parents pursue a dynamic rather than fixed balance between safety and expansion and between guidance and autonomy [ 4].

Future research should look at these weaknesses of the actual safety net expansions, and reach conclusions about possible policy improvements.