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When I wonder how that fascination arose, Höller talks about entomology being a safe surrogate for his real life-long passion, which is songbirds.
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The development of safe surrogates of diazo carbonyl compounds while maintaining the ease of accessing the corresponding metal carbenes would address this debilitating issue and provide substantial benefit to synthetic practices.
Since there is neither a single definition of QoC nor a single method to measure QoC, we used the six desired goals of the health system effective, efficient, accessible, acceptable/patient centred, equitable and safe 8 as surrogate indicators of QoC for the purpose of conducting the literature searches.
Before we roll out any vaccine to the entire population, we need to ensure that it is both effective and safe and not just rely on surrogate markers.
It all seems sufficiently safe and diverting to serve as a surrogate baby sitter, while perhaps just strange enough to appeal to hung-over adult hipsters.
Preclinical studies of the type described in this report must be combined with surrogate imaging agents to establish safe starting activity levels for phase I dose escalation trials.
But Upward Bound works because it gives students a safe space where they can have a surrogate family.
The success of chemopreventive approach depends on the recognition of high-risk subjects, the development of novel and safe agents, and the identification of new surrogate endpoint biomarkers using molecular pathways and new targets of drugs activity.
Adults whose "natural" route to parenthood is blocked – for medical reasons; because they are gay and so on – can find myriad websites telling them they have the "right to parent" and, in the process, sidelining the right of surrogate-born children to have safe and secure parenting.
The key idea is to iteratively construct surrogates which quickly explore the safe domain and focus on the limit-state surface in its final stage.
(Norovirus is nearly impossible to cultivate in the lab, and it's safer to use the surrogates).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com