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The injection of bulking agents is an attractive treatment option for SUI in view of their safe side effect profile.
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While the t-PA treatment of blood clot is considered to be safe, side effects occurring in some patients have raised major concerns about the safety and the efficacy of t-PA treatment.
The release of newer antiretrovirals with safer side effect profiles and effectiveness against resistant virus means that most patients who are adherent can suppress HIV RNA in plasma.
This review of the current literature highlights the versatility of the GR in forming homodimer interactions, as well as the ability to bind to alternate nuclear receptors, and investigates the potential implications such varying GR dimer conformations may have for the design of GR ligands with a safer side effect profile.
Codeine has been the mainstay of treatment of post-craniotomy pain in our institution, due to its safer side effect profile when compared to more potent opioids.
13, 14 The results of the studies evaluating PLD have never matched those of its parent drug, but with a safer side effect profile, in certain circumstances, it is preferable.
32 An open-label, non-controlled Phase I trial by Rodriguez et al, 16 done on 15 rheumatoid arthritis patients, showed good therapeutic response that lasted for 4 weeks after the last dose of Itolizumab and with a safer side effect profile.
Risperidone was effective and demonstrated a safe side-effect profile.
Such drugs have shown clinical efficacy in the treatment of respiratory disease while having a considerably safer side-effect profile in comparison with theophylline, particularly because there are no reported drug interactions with PDE4 inhibitors, a feature that complicates the use of theophylline.
Statins are generally quite safe, but side effects may include muscle pain and fatigue.
Supplement manufacturers are permitted to use advertisements and testimonials claiming that their products are "all natural" and "completely safe, without side effects".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com