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Eric has internalized his parents' desire for fail-safe certainty.
Snuggled between my mum and dad I feel completely safe, enveloped in the certainty that whatever demons dwell in my dreams they cannot harm me because Mum and Dad are at my side.
About the only item on the dinner menu that can be judged with some degree of certainty as safe is the gallon jug of Horilka vodka that Marina's spirited 61-year-old mother has brought.
The FDA defines "safe" as "a reasonable certainty in the minds of scientists that the substance is not harmful under its intended conditions of use".
Given the challenges of developing active vaccines that potentially target self-epitopes and thus could induce autoimmune disease, passive immunotherapies, which appear to be relatively safe and have more certainty regarding target engagement, are clearly ideal ways to move forward to evaluate potential efficacy in AD.
In the absence of certainty, the safest and arguably most healthy approach to nutrition falls back on variety – of food groups, macronutrients, ingredients.
Stronger oversight will benefit the companies themselves and their investors, who, while continuing to prosper, should also thrive with the steady certainty that their safe investment will never go the way of the South Sea Co.
For instance, the safety factor approach results in an exposure limit [acceptable daily intake (ADI), reference dose (RfD)] generally presumed to be "safe" (e.g., having "reasonable certainty of no harm").
"We cannot say with any certainty that cellphones are either safe or not safe," Dr. Black said on CNN.
That may sound reasonable, but as the implosion of supposedly triple-A rated mortgage bonds during the crisis showed, it's difficult to know with certainty which assets are safe and which are not.
"But 80-90 percent of our investments are in Asia, Europe and Israel right now because they are actually countries where there's enough regulatory certainty that entrepreneurs feel safe starting token or blockchain companies there".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com