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The data was collected as a part of the hospital' s infection prevalence survey.
Acute phase proteins (APPs), such as Lactotransferrin [ 50], Haptoglobin [ 51], Serum amyloid A 2 [ 52] and coagulation factor XIII, were involved in physiologic reactions initiated early in the inflammatory process [ 53], and could be a response to S. sui s infection [ 54].
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Generally, the degree of gene response to RDV-O infection was lowest and the response to RDV-S infection was highest.
The degree of suppression by RDV-D84 infection was similar to that by RDV-O infection, and was less than that by RDV-S infection, whereas the degree of activation by RDV-D84 was higher than that by RDV-O infection and was similar to that by RDV-S infection.
For activated DEGs, the degree of response by RDV-D84 infection was generally higher than that by RDV-O infection, but was similar to that by RDV-S infection (Figure 5 and 6).
For a majority of suppressed DEGs, the degree of response by RDV-D84 infection was similar to that by RDV-O infection, but was lower than that by RDV-S infection (Figure 6).
The degree of gene activation by RDV-D84 infection was closer to that by RDV-S infection than to that by RDV-O infection, whereas the degree of gene suppression by RDV-D84 was closer to that by RDV-O infection.
Differentially expressed (DE) mRNAs identified in response to MAB-R and MAB-S infection.
Differentially expressed (DE) miRNAs identified in response to MAB-R and MAB-S infection.
The IL-1β and IL-8 responses were found to be more robust, with higher levels detected in response to MAB-S infection (Fig. 4).
Bar plots show the percentage of dead macrophages in response to MAB-R and MAB-S infection, as well as among uninfected controls.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com