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These nanoformulations played a key and potential role to load nanomedicine to check the cancer cell inhibition and rupture upon incubation for 24 h in CO2 incubator.
Defects in K5 K14 filament network architecture cause basal keratinocytes to become fragile, and account for their rupture upon exposure to mechanical trauma.
The method is based upon photosensitizers localized in the membranes of endocytic vesicles which create membrane rupture upon light exposure by generating reactive oxygen species (ROS), predominantly singlet oxygen (1O2).
In contrast, cuti-1 RNAi) cuti-1 RNAit rupture upon handling or wormssuspendod inotateruptureffer (data not shown).
If liposomes are deposited on freshly cleaved mica and allowed to fuse and rupture upon contact with the mica surface for 20 min, planar lipid bilayers with thickness of 5.0 5.5 nm are formed (Figure S5 A,B).
Liposomes reconstituted with Ub oligomers were then deposited on freshly cleaved mica for 20 min and allowed to fuse and rupture upon contact with the mica surface forming planar lipid bilayers, as previously described [65].
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Keratin filaments impart mechanical strength to keratinocytes, without which the cells become fragile and prone to rupturing upon physical stress [50].
They display a fragile cuticle that often ruptures upon handling, the cuticle surface is disorganized, and collagens such as DPY-7 are retained within the hypodermis instead of being secreted to the cuticle.
The counter-intuitive finding of an increased risk of asthma is believed to result from pollen grains swelling and rupturing upon contact with rainwater.
For acidic bulk water (≤ pH 2.0), the lifetime of the liquid marbles was less than 10 s, and the liquid marbles quickly ruptured upon contact with the water.
Maintaining constant pressure on an attached syringe filled with additional simulated purulence allowed for a continuous effluent of purulent material when the simulated abscess ruptured upon incision.
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