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The imbalance in the exclusion of patients from the FAS1000mg was due to the design of this study, which specified different rules of discontinuation for the two groups.
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However, due to the low number of discontinuation events we are unable to rule out the possibility of a clinically important effect with SSRI treatment as the S allele may be associated with up to a 42% increase in odds of discontinuation or a 17% reduced odds (OR 1.09, 95% CI 0.83 1.42).
42 However, we cannot rule out the possibility of unmeasured factors influencing our calculations, as the accuracy of assessment of discontinuation by monitoring of prescriptions is unknown.
X-axis: causes of discontinuation.
Dr. Saltz says tapering slowly makes discontinuation syndrome far less likely to happen, but every time I've stopped or reduced my meds through tapering, I've still experienced symptoms of discontinuation to some extent.
Complications of discontinuation of therapy were noted.
Table S5 : Predictors of discontinuation and reinitiation.
Rules of the game.
Establish rules of engagement.
The rules of competition.
The end point was determined through a discontinuation rule of 20 videos.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com