The differentiability of the projection allows for the computation via the chain rule of design sensitivities of responses of interest, and therefore it allows for the use of robust and efficient gradient-based optimization methods.
According to the authors' description, the modified ATS rule can serve as a useful counterpart to the prediction by Fine et al. The modified ATS rule was good in terms of sensitivity (89.9%) and the area under the receiver operator curve graph (0.823) for predicting 14-day ICU admission in HCAP patients.
That was the same problem the Paphitou rule encountered, as performance in the original single-center study was quite predictive, but when we attempted to validate it in a multicenter data set, the rule lost a significant amount of sensitivity and specificity.
This table shows single-condition rules and rules which met our primary criteria of sensitivity and PPV ≥ 90%, and additionally had specificity and NPV ≥ 85%.
For each of the 18 models standard statistics, e.g. numbers of rules, sensitivity, specificity, accuracy, etc., are provided.
Association of CPSF6 with RTC/PIC below the level of sensitivity cannot be ruled out for the CPSF6-negative cytoplasmic RTC/PIC in this experimental system, however.
What is the sensitivity change rule of the force control parameters?
In the following section, these dynamic changes are quantitatively analyzed to grasp the sensitivity change rule of each parameter under the nine selected working conditions.
We estimate that Shewhart's control rules have sensitivity of 30 and 33% for manic and depressive episodes, so that approximately one-third of episodes are detected in advance.
In diagnostic tests and clinical prediction rules a sensitivity of 100% is hard to achieve, because patients present at different stages in the evolution of their illness.
